Environmental monitoring
Connect room conditions, sensors, manual backup readings, viable air and surface sampling, particle counts, alerts, excursions, and investigations.
Evaluating one vendor? Read the Simplifi 797 comparison or the PharmacyStars comparison.
Pharmacy compliance software comparison
Compare CompliRx, Simplifi 797 and PharmacyStars against your actual workflows.
Build a shortlist using documented capabilities, then test the same record and workflow in each platform. This comparison covers CompliRx, Simplifi 797 and PharmacyStars, with links to vendor and integration-partner sources.
Limited pilot pricing: $399 per month for 90 days, with guided configuration and workflow review.
Published capabilities and what to verify
Competitor entries summarize vendor and integration-partner publications, not independent product tests. Simplifi 797 sources reviewed September 6, 2026. Compounding360 sources reviewed November 3, 2026. “Ask vendor” means the sources we reviewed did not describe that area. It does not mean the product lacks it. Confirm current packaging, integration scope and commercial terms directly with each vendor.
| Workflow area | CompliRx | Simplifi 797 | PharmacyStars Compounding360 | Test in every product |
|---|---|---|---|---|
| Recurring compliance tasks | Daily, weekly, monthly and yearly room and PEC checklists generated from templates; each item records who did the work, when, and the products used. | Describes automated daily, weekly and monthly compliance tasks. [1] | Ask vendor | Show a missed daily item and how it is corrected without rewriting history. |
| Training and competency | Role- and function-based assignments, SCORM courses, outside certificates; garbing, gloved-fingertip and media-fill runs with incubation tracking. | Describes staff training and competency management and continuing-education modules. [1][2] | Described as including expert training, a learning management system and competency quizzes. [4] | Retrieve one employee’s course completions and practical qualification results separately. |
| Environmental monitoring | Native connections to Monnit, SensorPush, SafetyCulture, Dickson and TempStick; offline alerts; manual backup readings; viable sampling and particle counts. | Describes environmental monitoring through a Sonicu integration, with alerts for out-of-range conditions. [1] | Sonicu documents a SoniCloud integration with Compounding360 at a multi-site health system. [3] | Which sensors are supported, and what happens when one stops reporting? |
| SOPs and documents | Versioned SOPs with review and approval, password-confirmed signatures, superseded editions and staff acknowledgments. | Ask vendor | Described as a QMS loaded with industry expert SOPs. [4] | Show the SOP version in effect on a past date and who acknowledged it. |
| CAPA and investigations | CAPA owner, root-cause method, action items with due dates and an effectiveness check; microbial excursions can open a CAPA by policy. | Ask vendor | Quality reports are described as covering CAPAs. [3] | Trace a failed result through investigation, action and effectiveness review. |
| Equipment | Equipment registry with calibration and maintenance due dates, certification reports and reminders. | Ask vendor | Quality reports are described as including equipment lists. [3] | Show a hood’s certification history and its next due date. |
| Reporting and inspection preparation | Compliance score across 11 categories, FDA six-system inspector view, mock inspections, Form 483 tracking and date-range PDF or Excel exports. | Describes real-time compliance tracking and reporting. [2] | Described as retrieving board-requested USP <795>, <797> and <800> data and quality and trending reports. [3] | Produce the records an inspector asks for, scoped to one room and date range. |
| Published pricing | 90-day guided pilot at $399 per month. Pilot terms | Ask vendor | Ask vendor | Request a written quote separating subscription, devices, integrations, implementation and renewal. |
- Wolters Kluwer, Simplifi 797 FAQ
- Wolters Kluwer, Simplifi 797 product page
- Sonicu, Compounding360 integration (Dec 2024)
- EQUASHIELD and Pharmacy Stars joint release (Dec 2024)
CompliRx entries describe the current product; see the workflow catalog and supported integrations.
Use the same acceptance criteria for every vendor
- Trace an out-of-range result through acknowledgment, investigation, disposition and any linked CAPA.
- Retrieve an employee’s competency evidence and the SOP version used when training occurred.
- Test exports, historical record access and migration reconciliation before retiring the previous system.
- Request a written quote separating subscription, devices, integrations, implementation, training and renewal terms.
Use the electronic-record review checklist to assess applicable controls. Published features and a successful demo do not replace your intended-use validation.
Why CompliRx
One operational record from daily task to inspection evidence
The strongest compliance system is not the one with the longest feature list. It is the one your staff can execute correctly, your designated person can oversee, and your pharmacy can explain under inspection.
Personnel qualification
Track role-based training, garbing, gloved-fingertip sampling, media fills, competencies, credentials, due dates, and supporting evidence.
Daily compliance work
Turn recurring cleaning, monitoring, review, and follow-through into attributable work that opens directly to the record requiring action.
Quality and CAPA
Preserve the connection from a failed result or excursion through investigation, corrective action, ownership, effectiveness review, and closure.
Inspection retrieval
Move from a dashboard indicator to the underlying record, signature, attachment, history, and export without reconstructing the story from separate systems.
A safer evaluation
Prove the platform with your own facility
A sales demonstration cannot prove whether a platform fits your rooms, people, schedules, sampling plan, or inspection requests. The CompliRx pilot is structured around real workflows and measurable retrieval.
Map the facility
Configure rooms, classifications, pressure relationships, equipment, personnel, and the monitoring program around the way the pharmacy actually operates.
Bring forward current records
Identify controlled documents, active qualifications, equipment evidence, open deviations, sampling plans, and recurring work that must remain current.
Run real workflows
Use the pilot for actual daily logs, environmental monitoring, sampling, review, and retrieval instead of judging fit from a canned demonstration.
Test evidence retrieval
Select representative requests and verify that staff can retrieve the source record, attribution, review, attachments, and follow-through quickly.
What to require from your next compliance platform
Every alert opens the exact record requiring action
Personal work stays separate from administrative oversight
Facility data remains isolated by tenant and location
Electronic attribution and review history remain visible
Sampling supports in-house and outsourced execution
Sensor outages have controlled manual backup workflows
Failed results remain connected to investigation and CAPA
Inspection exports trace back to source evidence
Frequently asked questions
What is a practical alternative to Simplifi 797 or PharmacyStars?
CompliRx is purpose-built compliance operations software for 503A and 503B compounding pharmacies evaluating an alternative to Simplifi 797 or PharmacyStars. It connects environmental monitoring, cleaning, personnel qualification, controlled documents, equipment, CAPA, and inspection preparation in one facility record.
Who is CompliRx designed for?
CompliRx is designed for compounding pharmacy owners, designated persons, pharmacists, technicians, and quality teams that want to operate their own compliance program with clearer daily work and faster evidence retrieval.
What does the CompliRx pilot include?
The limited 90-day pilot is $399 per month and includes platform access, guided facility configuration, workflow review, and direct implementation support. Pilot scope and terms are confirmed before activation.
Can CompliRx replace spreadsheets and paper logs?
CompliRx can digitize recurring work, readings, sampling records, qualifications, approvals, and linked evidence. A pharmacy should validate its configured workflows and migration plan before retiring controlled paper or spreadsheet processes.
Does CompliRx guarantee USP compliance?
No software guarantees compliance. CompliRx supports consistent execution, attribution, oversight, investigation, and inspection readiness while the pharmacy remains responsible for professional decisions, policies, validation, and applicable requirements.
CompliRx is not affiliated with or endorsed by Wolters Kluwer, Simplifi 797, PharmacyStars, or Compounding360. Product names are trademarks of their respective owners.
See whether CompliRx fits your real operation.
Run one facility through a guided 90-day pilot, execute real workflows, and test inspection retrieval before making a broader commitment.